Apoptosis without decrease of cell DNA content
نویسندگان
چکیده
منابع مشابه
Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma.
To elucidate the relationship between tumor genesis and the mitochondrial energy metabolism in renal neoplasms, we studied three individual enzyme activities of the oxidative phosphorylation, two components of the Krebs cycle and the mitochondrial DNA content of renal carcinomas including 29 conventional, five papillary, two unclassified carcinomas with sarcomatoid features and one collecting d...
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Hematoxylin-eosin staining, the TUNEL method for in situ detection of the intranuclear DNA fragmentation, which indicates apoptosis, and electron microscopy were used to study the morphologic changes in specimens from the eyes of 8 patients with secondary glaucoma and 2 normal control eyes to evaluate our hypothesis that apoptosis causes a decrease in retinal ganglion cells in human glaucomatou...
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Apoptotic cells possess specific morphological and biochemical markers. Various methods have been developed to detect apoptosis based on these markers. One of the most common is the fragmentation of genomic DNA. In addition to electrophoresis for the identification of the characteristic 200 base pair ladders and terminal deoxyribonucleotidyltransferase-mediated dUTP-biotin nick end-labeling, DN...
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Background & Aim: Chlorine has been known as a mucus membranes and respiratory tract irritant. This gas can increase free radicals which cause cell damage. The aim of the present study was to measure DNA content and cell cycle in white blood cells after chronic chlorine poisoning. Materials & Methods: A clinical experimental study was carried out on 80 male mice(40 mice as sample and 40 as ...
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In the past 12 years, since the first description of C. elegans germ cell apoptosis, this area of research rapidly expanded. It became evident that multiple genetic pathways lead to the apoptotic demise of germ cells. We are only beginning to understand how these pathways that all require the CED-9/Bcl-2, Apaf-1/CED-4 and CED-3 caspase core apoptosis components are regulated. Physiological apop...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1995
ISSN: 0014-5793
DOI: 10.1016/0014-5793(95)00532-e